UPDATE 5:22 p.m. The intersection has been opened to traffic, Ohio 4 closed south of Ohio 2 for separate semi rollovers.
UPDATE 4:00 p.m. Erie County coroner Brian Baxter has been called to the scene.
Perkins police and fire on scene with the Ohio State Highway Patrol. A Sandusky fire department squad has been called in for mutual aid.
Check back for updates here and in Saturday's Sandusky Register