The Columbus Dispatch reports about 3,200 people have called the line this year, and there was a noticeable increase from September to October, the month Ohio's third casino opened in Columbus.
An Ohio Casino Control Commission official says most calls are from people whose gambling caused serious personal or financial problems.
A study earlier this year estimated about 250,000 Ohio adults, just less than 3 percent, are problem gamblers or at risk of gambling problems.
Ohioans can opt to be voluntarily banned from entering casinos, and 146 people have made that request so far.
Some of the taxes and fees paid by casinos go toward prevention efforts such as the hotline.