Roy Kilgore, 67, was transported to Mercy Willard Hospital, where he was pronounced dead.
Kilgore was riding a bicycle when at about 11:30 a.m. he exited the Blossom Center and struck the rear of a passing tractor-trailer, police said. He was ejected from the bike.
The tractor-trailer was headed east on Walton Avenue. Police said the crash remains under investigation.